This brief provides information and resources on trauma-informed care (TIC) for staff of adolescent pregnancy prevention programs (APP). The first section of the brief describes how a history of trauma can impact youth’s well-being. The second section summarizes the frequency of trauma histories among youth likely to attend APP programs. The third section presents principles of trauma-informed care that APP staff can incorporate into their programming to meet the needs of youth with trauma histories. The fourth section introduces APP staff to three steps to incorporate TIC principles into programming. The fifth section provides a tool for staff to assess their use of such care. In the appendix, there is a list of resources and organizations for those seeking more information.